Korean Journal of Geriatrics & Gerontology

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Table. 3.

Table. 3.

The management of strict blood pressure was superior to non-strict group in terms of major clinical outcomes

Chinese, Wei et al [9] SPRINT-Senior [10] STEP [11]
Year 2013 2016 2021
Participants 724 2,636 8,511
Age 76.6 (>70) 76.6 (>75, condition to walk alone) 66 (60-80)
BP criteria SBP≥160 mmHg SBP 160-199 mmHg SBP 140-190 mmHg
Study design Intensive (SBP≤140 mmHg)
Standard (SBP 141-150 mmHg)
Strict (SBP<120 mmHg)
Moderate (SBP<140 mmHg)
Standard 130-150 mmHg
Intensive 110-130 mmHg
Primary outcomes Composites of fatal/non-fatal stroke, AMI, CV death Composite of AMI, ACS, HF, or CV death Composite of stroke, ACS, ADHF, coronary revasc, AF, CV death
Follow-up 60 months 4 years 3.34 years
Major findings Intensive group; superior Intensive group; superior Intensive group; superior

SPRINT, Systolic Blood Pressure Intervention Trial; STEP, Systolic blood pressure intervention in the elderly hypertensive patients; BP, blood pressure; SBP, systolic blood pressure; AMI, acute myocardial infarction; CV, cardiovascular; ACS, acute coronary syndrome; HF, heart failure; ADHF, acute decompensated heart failure; AF, atrial fibrillation.

Korean J Clin Geri 2023;24:100-103 https://doi.org/10.15656/kjcg.2023.24.3.100
© 2023 Korean J Clin Geri