Korean Journal of Geriatrics & Gerontology

Indexed in /covered by CAS, KoreaScience & DOI/Crossref:eISSN 2383-5699   pISSN 1229-6538

Table. 2.

Table. 2.

Factors associated with serum uric acid level in female and male participants

Female Male
Simple linear regression Multiple linear regression Simple linear regression Multiple linear regression
Mean difference (95% CI) P Adjusted mean difference (95% CI) P Mean difference (95% CI) P Adjusted mean difference (95% CI) P
AMD
No Reference - Reference - Reference - Reference -
Yes 0.01 (−0.07 to 0.09) 0.874 −0.06 (−0.13 to 0.02) 0.153 −0.26 (−0.36 to −0.16) <0.001 −0.20 (−0.29 to −0.10) <0.001
Age (year)
40 to <60 Reference - Reference - Reference - Reference -
60 to <80 0.14 (0.08-0.20) <0.001 −0.02 (−0.10 to 0.05) 0.519 −0.23 (−0.31 to −0.15) <0.001 −0.24 (−0.33 to −0.16) <0.001
≥80 0.37 (0.20-0.55) <0.001 0.02 (−0.15 to 0.19) 0.813 −0.38 (−0.64 to −0.12) 0.004 −0.53 (−0.81 to −0.26) <0.001
Education
Elementary school or less Reference - Reference - Reference - Reference -
Middle school −0.02 (−0.12 to 0.08) 0.635 0.15 (0.05-0.24) 0.002 0.09 (−0.08 to 0.25) 0.318 0.01 (−0.15 to 0.16) 0.920
High school −0.12 (−0.19 to −0.04) 0.002 0.13 (0.04-0.21) 0.004 0.21 (0.08-0.34) 0.002 0.06 (−0.06 to 0.19) 0.321
College or above −0.20 (−0.27 to −0.13) <0.001 0.13 (0.03-0.23) 0.010 0.34 (0.21-0.47) <0.001 0.16 (0.03-0.29) 0.016
Household income
Low Reference - Reference - Reference - Reference -
Mid-low −0.10 (−0.19 to −0.01) 0.029 0.02 (−0.07 to 0.11) 0.622 −0.02 (−0.16 to 0.12) 0.788 −0.10 (−0.23 to 0.04) 0.157
Mid-high −0.13 (−0.21 to −0.05) 0.002 0.03 (−0.06 to 0.11) 0.554 0.05 (−0.08 to 0.19) 0.444 −0.08 (−0.21 to 0.05) 0.237
High −0.13 (−0.21 to −0.05) 0.002 0.06 (−0.02 to 0.15) 0.156 0.13 (0.01-0.26) 0.037 −0.07 (−0.20 to 0.06) 0.305
Alcohol intake (g/day)
0 Reference - Reference - Reference - Reference -
<16 −0.03 (−0.10 to 0.03) 0.350 0.11 (0.04-0.17) 0.001 0.37 (0.20-0.54) <0.001 0.26 (0.09-0.42) 0.002
16-40 0.28 (0.14-0.43) <0.001 0.36 (0.22-0.51) <0.001 0.57 (0.39-0.75) <0.001 0.45 (0.27-0.63) <0.001
>40 0.44 (0.13-0.75) 0.006 0.47 (0.18-0.75) 0.001 0.55 (0.35-0.75) <0.001 0.46 (0.25-0.66) <0.001
Smoking
Never smoked Reference - Reference - Reference - Reference -
Ex-smoker 0.15 (0.02-0.27) 0.025 0.09 (−0.02 to 0.21) 0.116 0.19 (0.09-0.29) <0.001 0.11 (0.01-0.21) 0.028
Current smoker 0.24 (0.10-0.38) 0.001 0.15 (0.02-0.27) 0.026 0.13 (0.02-0.24) 0.021 0.01 (−0.10 to 0.12) 0.844
Physical activity
Low Reference - Reference - Reference - Reference -
Moderate −0.02 (−0.08 to 0.04) 0.515 0.04 (−0.01 to 0.10) 0.138 0.04 (−0.05 to 0.13) 0.352 0.04 (−0.05 to 0.13) 0.378
High −0.13 (−0.26 to −0.01) 0.031 −0.04 (−0.15 to 0.07) 0.487 0.06 (−0.07 to 0.20) 0.376 0.06 (−0.07 to 0.19) 0.390
Resistance exercise (/week)
0 times Reference - Reference - Reference - Reference -
1-3 times −0.06 (−0.15 to 0.02) 0.147 0.03 (−0.06 to 0.11) 0.546 0.04 (−0.07 to 0.14) 0.472 0.01 (−0.09 to 0.11) 0.853
≥4 times −0.03 (−0.14 to 0.09) 0.636 0.01 (−0.09 to 0.11) 0.860 0.01 (−0.09 to 0.12) 0.811 0.07 (−0.04 to 0.17) 0.209
Abdominal obesity
No Reference - Reference - Reference - Reference -
Yes 0.50 (0.44-0.57) <0.001 0.37 (0.31-0.43) <0.001 0.36 (0.28-0.44) <0.001 0.23 (0.16-0.31) <0.001
Elevated fasting glucose
No Reference - Reference - Reference - Reference -
Yes 0.26 (0.20-0.32) <0.001 0.07 (0.01-0.13) 0.014 0.00 (−0.08 to 0.08) 0.980 −0.14 (−0.22 to −0.07) <0.001
High triglycerides
No Reference - Reference - Reference - Reference -
Yes 0.50 (0.43-0.57) <0.001 0.33 (0.26-0.39) <0.001 0.49 (0.41-0.58) <0.001 0.38 (0.29-0.47) <0.001
Low HDL-cholesterol
No Reference - Reference - Reference - Reference -
Yes 0.31 (0.25-0.36) <0.001 0.14 (0.08-0.19) <0.001 0.26 (0.17-0.35) <0.001 0.13 (0.03-0.22) 0.008
Elevated blood pressure
No Reference - Reference - Reference - Reference -
Yes 0.19 (0.13-0.26) <0.001 0.07 (0.01-0.13) 0.034 0.26 (0.18-0.34) <0.001 0.16 (0.08-0.24) <0.001
Estimated GFR*
≥90 Reference - Reference - Reference - Reference -
60 to <90 0.41 (0.36-0.47) <0.001 0.42 (0.37-0.47) <0.001 0.41 (0.33-0.49) <0.001 0.46 (0.38-0.53) <0.001
<60 1.77 (1.52-2.01) <0.001 1.70 (1.45-1.96) <0.001 1.34 (1.08-1.61) <0.001 1.54 (1.29-1.80) <0.001

*Estimated GFR are represented in units of mL/min/1.73 m2. P values were obtained by linear regression model for complex survey design. AMD, age-related macular degeneration; HDL, high-density lipoprotein; GFR, glomerular filtration rates.

Korean J Geriatr Gerontol 2023;24:104-114 https://doi.org/10.15656/kjcg.2023.24.3.104
© 2023 Korean J Geriatr Gerontol