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The Relationship of Lean Body Mass and Osteoporosis in Postmenopausal Woman
Korean J Geriatr Gerontol 2013 Jun;14(1):32-38
Published online June 30, 2013
Copyright © 2013 The Korean Academy of Clinical Geriatrics.

Jeong Eun Yun, Seung Hye Lee, Youn Seon Choi, Kyung Sun Yang, Hyunduck Um, Seon Mee Kim, Joon Yong Lee, Seung Hwan Lee

Department of Family Medicine, Korea University Guro Hospital, Seoul, Korea
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: The relative contribution of lean mass and fat mass to the determination of bone mineral density(BMD) in postmenopausal women is a controversy. In this study, the impact of lean mass on BMD was examined, after the postmenopausal women were grouped by BMD level. Methods: The subjects were 100 postmenopausal women aged older than 50 and below 80 years old who visited a general hospital for medical check-up from July 2008 to November 2010. The lumbar spines and femur BMD T score were assessed with DEXA. And body fat mass and lean body mass were assessed with Inbody 720. Osteoporosis was defined as T score of any BMD lower than ?2.5 SD. Normal group was defined as T score greater than ?1 SD. They didn’t any disease and didn’t received hormone therapy or other medication that influence the bone density. Results: The prevalence of osteoporosis was 28% of this study. The mean age was 56.97±5.76. The results show that significant correlation between weight, BMI and The lumbar spines and femur BMD. The results of regression analysis with all subjects show that lean body mass, as independent variable, has significant determinants of BMD. In the multiple logistic regression, osteoporosis prevalence decreased 0.6 fold with 1kg increase in lean body mass (95% CI: 0.384~0.934). Conclusion: This study suggests that lean body mass rather than fat mass may be associated with BMD in postmenopausal women.
Keywords : Postmenopause, Osteoporosis, Fat mass, Lean mass

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