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The Association between Neurological Prognosis and Serum Glucose Level by Stroke Subtype in Acute Ischemic Stroke
Korean J Clin Geri 2017 Dec;18(2):82-86
Published online December 29, 2017;  https://doi.org/10.15656/kjcg.2017.18.2.82
Copyright © 2017 The Korean Academy of Clinical Geriatrics.

Tae-Won Kim, Jeong-Min So, Sung-Woo Chung, In-Uk Song

Department of Neurology, College of Medicine, The Catholic University of Korea, Incheon, Korea
Received June 5, 2017; Accepted August 29, 2017.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
Background: Studies evaluating the prognostic value of admission glucose level (AGL) by stroke subtypes are rare. We aimed to evaluate the association between AGL and short-term outcome by each stroke subtype.
Methods: We recruited 265 patients with acute infarction who were consecutively admitted to our hospital after acute stroke. We classified the patients into lacunar, large artery artherosclerosis (LAA) or cardioembolic infarction according to the TOAST stroke classification. AGL were measured at admission. The National Institutes of Health Stroke Scale (NIHSS) were evaluated initially and at 5 admission days.
Results: Fifty patients were lacunar group, 190 were LAA group and 25 were cardioembolic group. All enrolled patients with higher AGL had significantly worse functional outcomes in acute stage compared to the low AGL group (P=0.005). In respect to stroke suptype, AGL was significantly associated with worse functional outcome in acute stage only in LAA group (P=0.002). There were no association between AGL and functional outcome in lacunar or cardioembolic infarction.
Conclusion: The prognostic implication of AGL in acute ischemic stroke was different depending on each stroke subtype. Although AGL predicted worse functional outcome only in LAA group, it did not associate with functional outcome in the lacunar or cardioembolic infarction.
Keywords : Admission glucose level, Acute stroke, Functional outcome
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June 2018, 19 (1)